Cardiovascular disease

Interplay Between Plasma Glycine and Branched-Chain Amino Acids Contributes to the Development of Hypertension and Coronary Heart Disease

M. Dziedzic et. al, Hypertension, 2024
Risk prediction, Mortality & multi-morbidity

Data-driven identification of predictive risk biomarkers for subgroups of osteoarthritis using interpretable machine learning

R. Nielsen et. al, Nature Communications, 2024
Diabetes, Risk prediction

Development and External Validation of Machine Learning Models for Diabetic Microvascular Complications: Cross-Sectional Study With Metabolites

F. He et. al, Journal of Medical Internet Research, 2024
Diabetes

Novel Serum and Urinary Metabolites Associated with Diabetic Retinopathy in Three Asian Cohorts

D. Quek et. al, Metabolites, 2021
Cardiovascular disease

Remnant Cholesterol, Not LDL Cholesterol, Explains Peripheral Artery Disease Risk Conferred by apoB: A Cohort Study

B. Wadström et. al, Arteriosclerosis, Thrombosis, and Vascular Biology, 2024
Ageing & dementia, Methods

Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data

M. Sluiskes et. al, BMC Medical Research Methodology, 2024
Kidney disease, Exposome & nutrition

Plasma Levels of Polyunsaturated Fatty Acids and Adverse Kidney Outcomes

H. Koh et. al, American Journal of Kidney Diseases, 2024
Exposome & nutrition

Genetic correlation between circulating metabolites and chalazion: a two-sample Mendelian randomization study

X. Zhang et. al, Frontiers in Molecular Biosciences, 2024
Diabetes

A two-sample Mendelian randomization study explores metabolic profiling of different glycemic traits

T. Wong et. al, Communications Biology, 2024
Diabetes

SGLT2 inhibition, high-density lipoprotein, and kidney function: a mendelian randomization study

Z. Wang et. al, Lipids in Health and Disease, 2024
Diabetes

Nuclear magnetic resonance-based metabolomics with machine learning for predicting progression from prediabetes to diabetes

J. Li et. al, eLife, 2024
Cancer

Metabolomic landscape of overall and common cancers in the UK Biobank: A prospective cohort study

C. Hu et. al, International Journal of Cancer, 2024
Exposome & nutrition, Cardiovascular disease

Muesli Intake May Protect Against Coronary Artery Disease

J. Park et. al, JACC: Advances, 2024
Exposome & nutrition, Obesity & bodyweight

The association between body mass index and metabolite response to a liquid mixed meal challenge: a Mendelian randomization study

D. Hughes et. al, The American Journal of Clinical Nutrition, 2024
Ageing & dementia

Mendelian Randomization of Blood Metabolites Suggests Circulating Glutamine Protects Against Late-Onset Alzheimer’s Disease

F. Ramadan et. al, Journal of Alzheimer’s Disease, 2024