Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT

Researchers identified 35 circulating metabolites associated with prostate cancer presence, but found no evidence of causality for those 14 testable with MR.

Thus, the 14 MR-tested metabolites are unlikely to be mechanistically important in prostate cancer risk. Impact: The metabolome provides a promising set of biomarkers that may aid prostate cancer classification.