A new study has identified 26 potentially harmful DNA variations that could alter a person’s CVD and diabetes risk.
A new exome sequencing study analysed a unique Finnish gene pool to identify the deleterious alleles and variations in DNA that might predispose certain individuals to diseases such as CVDs.
The comprehensive study was conducted by researchers at Washington University School of Medicine, St. Louis, in collaboration with the University of California, Los Angeles, the University of Michigan and Institute for Molecular Medicine Finland. The study analysed exome sequence data of nearly 20,000 individuals from Finland together with 64 clinically relevant quantitative traits and identified 26 potentially harmful DNA variations associated with cardiovascular and metabolic health. Of the 26 DNA variations identified, 19 are either unique to Finnish individuals or over 20 times more frequent in Finland compared to elsewhere in Europe.