Inflammatory diet and preclinical cardiovascular phenotypes in 11–12 year-olds and mid-life adults: A cross-sectional population-based study

Researchers investigated pro-inflammatory diet as a potential modifiable risk factor for cardiovascular disease.

Two inflammatory diet scores, one derived from published evidence of associations with C-reactive protein and the other one based on Nightingale's inflammatory biomarker, GlycA, were analysed in the Child Health CheckPoint Study at adolescence and adulthood. In adults, both inflammatory diet scores showed small associations with adverse cardiovascular function and microvascular structure. Little evidence was observed in children. These findings support cumulative adverse effects of a pro-inflammatory diet on preclinical cardiovascular phenotypes across the life course.