Sex and puberty-related differences in metabolomic profiles associated with adiposity measures in youth with obesity

This study aimed to determine associations between adiposity measures and metabolomic profiles with increased cardiometabolic risks in youth with obesity using the participants from COBRA study.

Nightingale's metabolic profiles were assessed against adiposity measures and puberty staging. As a results, increased adiposity measures, especially in post-pubertal males, were associated with distinct patterns in metabolomic profiles.