Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

The findings of this study verify the association between rs10911021 and coronary heart disease in patients with type 2 diabetes.

While the genetic variant did not associate with glutamine and other quantified amino acids, there was an effect on several HDL particle traits specifically for diabetic patients.