Methods, Risk prediction

Machine learning for comprehensive interaction modelling improves disease risk prediction in the UK Biobank

H. Julkunen et. al, 2024
Maternal & child health, Psychiatric disorders

Maternal Antenatal Depression Is Associated With Metabolic Alterations That Predict Birth Outcomes and Child Neurodevelopment and Mental Health

P. Girchenko et. al, Biological Psychiatry, 2024
Exposome & nutrition, Maternal & child health

Childhood Nutritional Factors and Cardiometabolic Outcomes at 9–11 y of Age: Findings from the ROLO Longitudinal Birth Cohort Study

S. Callanan et. al, The American Journal of Clinical Nutrition, 2024
Cardiovascular disease, Exposome & nutrition

Blood metabolites mediate effects of breakfast skipping on heart failure via Mendelian randomization analysis

L. Lv et. al, Scientific Reports, 2024
Exposome & nutrition, Mortality & multi-morbidity

Plasma n6 polyunsaturated fatty acid levels and risk for total and cause-specific mortality: A prospective observational study from the UK Biobank

W. Harris et. al, The American Journal of Clinical Nutrition, 2024
Ageing & dementia

Contrasting association pattern of plasma low-density lipoprotein with white matter integrity in APOE4 carriers versus non-carriers

Z. Ye et. al, Neurobiology of Aging, 2024
Methods, Risk prediction

An open-source framework for end-to-end analysis of electronic health record data

L. Heumos et. al, Nature Medicine, 2024
Diabetes, Exposome & nutrition

Higher docosahexaenoic acid proportions in blood are inversely associated with the prevalence of prediabetes: Evidence from the UK Biobank

J. Schuchardt et. al, Nutrition Research, 2024
Cardiovascular disease

Plasma metabolites, systolic blood pressure, lifestyle, and stroke risk: A prospective cohort study

C. Zhang et. al, International Journal of Stroke, 2024
Cardiovascular disease, Exposome & nutrition

Circulating ketone bodies, genetic susceptibility, with left atrial remodeling and atrial fibrillation: A prospective study from the UK Biobank

N. Zhang et. al, Heart Rhythm, 2024
Cancer, Obesity & bodyweight

Causal Association of Adipose Tissue with Bladder Cancer and the Mediating Effects of Circulating Metabolites: A Mendelian Randomization Study

S. Yang et. al, Journal of Cancer, 2024
Cardiovascular disease

Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis

B. Gigante et. al, International Journal of Cardiology, 2024
Methods, Risk prediction, Mortality & multi-morbidity

Penalized reduced rank regression for multi-outcome survival data supports a common metabolic risk score for age-related diseases

M. Sluiskes et. al, 2024
Exposome & nutrition, Psychiatric disorders

Plasma Polyunsaturated Fatty Acid Levels and Mental Health in Middle-Aged and Elderly Adults

Y. Li et. al, Nutrients, 2024
Inflammation & immunity

Integrative multi-omics analysis to gain new insights into COVID-19

S. Eshetie et. al, Scientific Reports, 2024