Ageing & dementia

Assessing the causal role of lipid metabolites in Alzheimer's disease: A mendelian randomization study

H. Hu et. al, The Journal of Prevention of Alzheimer's Disease, 2025
Obesity & bodyweight

Sex-specific metabolic signatures of adiposity associated with clinical biomarkers in the UK Biobank

C. Papagiannopoulos et. al, 2025
Cardiovascular disease

(Apo)Lipoprotein Profiling with Multi‐Omics Analysis Identified Medium‐HDL‐Targeting PSRC1 with Therapeutic Potential for Coronary Artery Disease

Y. Li et. al, Advanced Science, 2025
Psychiatric disorders, Methods

Bootstrap inference and machine learning reveal core differential plasma metabolic connectome signatures in major depressive disorder

H. Pan et. al, Journal of Affective Disorders, 2025
Ageing & dementia, Exposome & nutrition

Associations Between Leisure‐Time Physical Activity and Metabolomics‐Based Markers of Biological Aging in Late Midlife: Short‐Term and Long‐Term Follow‐Up

K. Ruutu et. al, Aging Cell, 2025
Cardiovascular disease

Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease

L. Ao et. al, Journal of Lipid Research, 2025
Exposome & nutrition

Longitudinal associations of diet quality with serum biomarkers of lipid and amino acid metabolism from childhood to adolescence: the PANIC study

S. Laamanen et. al, British Journal of Nutrition, 2025
Exposome & nutrition

Association of nuclear magnetic resonance-based metabolomics with bone health in the UK Biobank

J. Cai et. al, Bone, 2025
Inflammation & immunity, Exposome & nutrition

Plasma Metabolite Profiles Linked to EAT‐Lancet Diet and Risk of Inflammatory Bowel Disease: A Prospective Cohort Study From UK Biobank

X. Ye et. al, Molecular Nutrition & Food Research, 2025
Cancer

Blood metabolic biomarkers and colorectal cancer risk: results from large prospective cohort and Mendelian randomisation analyses

F. Yuan et. al, British Journal of Cancer, 2025
Exposome & nutrition

Metabolomic and Proteomic Signatures of Ultra-processed Foods Are Positively Associated with Adverse Liver Outcomes

L. Zhao et. al, The Journal of Nutrition, 2025
Exposome & nutrition

Deciphering the Relationship Between Circulating Metabolites and Osteoarthritis: A Comprehensive Genetic Correlation and Mendelian Randomization Studies

G. Yang et. al, International Journal of Medical Sciences, 2025
Inflammation & immunity

Metabolic signature of COVID-19 progression: potential prognostic markers for severity and outcome

H. Nguyen et. al, Metabolomics, 2025
Ageing & dementia, Mortality & multi-morbidity

Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality risk

A. Zalesky et. al, Nature Communications, 2025
Genetics

Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers

D. Van Der Meer et. al, Nature Communications, 2025