Genetics

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

A. Gallois et. al, Nature Communications, 2019
Medicines & trials, Exposome & nutrition

The Effects of a Mediterranean Diet Intervention on Targeted Plasma Metabolic Biomarkers among US Firefighters: A Pilot Cluster-Randomized Trial

M. Sotos-Prieto et. al, Nutrients, 2020
Psychiatric disorders

Investigating Causality Between Blood Metabolites and Emotional and Behavioral Responses to Traumatic Stress: a Mendelian Randomization Study

C. Carvalho et. al, Molecular Neurobiology, 2019
Cardiovascular disease

A plasma proteogenomic signature for fibromuscular dysplasia

J. Olin et. al, Cardiovascular Research, 2019
Cardiovascular disease

Triglyceride-containing lipoprotein sub-fractions and risk of coronary heart disease and stroke: A prospective analysis in 11,560 adults

R. Joshi et. al, European Journal of Preventive Cardiology, 2020
Genetics

The influence of rare variants in circulating metabolic biomarkers

F. Riveros-Mckay et. al, PLOS Genetics, 2020
Ageing & dementia

The association of plasma fatty acids with hand and knee osteoarthritis: the NEO study

M. Loef et. al, Osteoarthritis and Cartilage, 2019
Maternal & child health

Sex differences in infant blood metabolite profile in association with weight and adiposity measures

S. Ellul et. al, Pediatric Research, 2020
Genetics, Methods

Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

V. Zuber et. al, Nature Communications, 2020
Diabetes, Kidney disease

Plasma Metabolomics Identifies Markers of Impaired Renal Function: A Meta-analysis of 3089 Persons with Type 2 Diabetes

N. Tofte et. al, The Journal of Clinical Endocrinology & Metabolism, 2020
Maternal & child health

Persistently High Levels of Maternal Antenatal Inflammation Are Associated With and Mediate the Effect of Prenatal Environmental Adversities on Neurodevelopmental Delay in the Offspring

P. Girchenko et. al, Biological Psychiatry, 2019
Psychiatric disorders

Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls

M. Bot et. al, Biological Psychiatry, 2019
Ageing & dementia

Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population

A. Hartley et. al, Clinical Endocrinology, 2019
Exposome & nutrition

Lifestyle‐Intervention‐Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter

M. Beekman et. al, Molecular Nutrition & Food Research, 2020
Medicines & trials

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas

J. Liu et. al, Nature Medicine, 2020