Ageing & dementia

Past or Present; Which Exposures Predict Metabolomic Aging Better? The Doetinchem Cohort Study

A. Smit et. al, The Journals of Gerontology: Series A, 2023
Cardiovascular disease, Ageing & dementia

Gut microbiota in combination with blood metabolites reveals characteristics of the disease cluster of coronary artery disease and cognitive impairment: a Mendelian randomization study

S. Xu et. al, Frontiers in Immunology, 2024
Genetics

Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrations

N. Sandholm et. al, Genome Medicine, 2022
Cancer, Cardiovascular disease, Diabetes, Exposome & nutrition, Kidney disease, Liver disease, Lung disease, Methods

Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers

S. Fang et. al, eLife, 2022
Diabetes, Kidney disease

Branched‐chain amino acid levels are inversely associated with incident and prevalent chronic kidney disease in people with type 2 diabetes

J. De Klerk et. al, Diabetes, Obesity and Metabolism, 2024
Exposome & nutrition

Associations of Lifestyle Patterns with Glucose and Lipid Metabolism in Finnish Adults at Increased Risk of Type 2 Diabetes

S. Manninen et. al, Molecular Nutrition & Food Research, 2024
Kidney disease, Risk prediction

Blood biomarkers improve the prediction of prevalent and incident severe chronic kidney disease

S. Nusinovici et. al, Journal of Nephrology, 2024
Cardiovascular disease, Diabetes, Inflammation & immunity

Towards clinical application of GlycA and GlycB for early detection of inflammation associated with (pre)diabetes and cardiovascular disease: recent evidence and updates

E. Fung et. al, Journal of Inflammation, 2023
Exposome & nutrition

Fish oil supplement use modifies the relationship between dietary oily fish intake and plasma n-3 PUFA levels: an analysis of the UK Biobank

J. Aldoori et. al, British Journal of Nutrition, 2024
Ageing & dementia, Risk prediction

Plasma metabolic profiles predict future dementia and dementia subtypes: a prospective analysis of 274,160 participants

Y. Qiang et. al, Alzheimer's Research & Therapy, 2024
Diabetes, Genetics

Hyperglycemia and a Common Variant ofGCKRAre Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men

A. Stančáková et. al, Diabetes, 2012
Medicines & trials

Short-term treatment with high dose liraglutide improves lipid and lipoprotein profile and changes hormonal mediators of lipid metabolism in obese patients with no overt type 2 diabetes mellitus: a randomized, placebo-controlled, cross-over, double-blind

N. Peradze et. al, Cardiovascular Diabetology, 2019
Maternal & child health, Exposome & nutrition, Inflammation & immunity

Cross‐sectional associations between physical fitness and biomarkers of inflammation in children—ThePANICstudy

E. Haapala et. al, Scandinavian Journal of Medicine & Science in Sports, 2023
Inflammation & immunity

Blood metabolomic and transcriptomic signatures stratify patient subgroups in multiple sclerosis according to disease severity

A. Oppong et. al, iScience, 2024
Maternal & child health

Polyunsaturated fatty acids and intrahepatic cholestasis of pregnancy: a two-sample Mendelian randomization analysis

Q. Li et. al, 2024