Genetics

Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol

T. Roman et. al, The American Journal of Human Genetics, 2015
Methods

metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

A. Cichonska et. al, Bioinformatics, 2016
Medicines & trials, Genetics

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

P. Würtz et. al, Journal of the American College of Cardiology, 2016
Genetics

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase–Independent Effects

F. Drenos et. al, Circulation: Cardiovascular Genetics, 2016
Liver disease

Longitudinal study of circulating oxidized LDL and HDL and fatty liver: the Cardiovascular Risk in Young Finns Study

J. Kaikkonen et. al, Free Radical Research, 2015
Diabetes

Insulin resistance is associated with altered amino acid metabolism and adipose tissue dysfunction in normoglycemic women

P. Wiklund et. al, Scientific Reports, 2016
Genetics

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

J. Kettunen et. al, Nature Communications, 2016
Genetics, Diabetes

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

L. Lotta et. al, PLOS Medicine, 2016
Liver disease, Genetics

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism—The Young Finns Study

E. Raitoharju et. al, Scientific Reports, 2016
Obesity & bodyweight

Abdominal obesity and circulating metabolites: A twin study approach

L. Bogl et. al, Metabolism, 2015
Cardiovascular disease

Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

L. Engelbrechtsen et. al, Obesity Science & Practice, 2017
Genetics

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

M. Cannon et. al, G3 Genes|Genomes|Genetics, 2017
Cardiovascular disease, Diabetes

The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis

I. Seppälä et. al, Scientific Reports, 2017
Medicines & trials

Statin Effects on Metabolic Profiles

D. Kofink et. al, Circulation: Cardiovascular Genetics, 2017
Exposome & nutrition

Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

E. Org et. al, Genome Biology, 2017