Cardiovascular disease, Lung disease

PCSK9genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations

M. Holmes et. al, 2023
Genetics

Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity

B. Valcárcel et. al, Journal of The Royal Society Interface, 2014
Genetics

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

T. Tukiainen et. al, Human Molecular Genetics, 2011
Ageing & dementia, Risk prediction

Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk

L. Kuiper et. al, The Journals of Gerontology: Series A, 2023
Exposome & nutrition, Lung disease

Association of tobacco smoke exposure with metabolic profile from childhood to early adulthood: the Special Turku Coronary Risk Factor Intervention Project

M. Lehtovirta et. al, European Journal of Preventive Cardiology, 2023
Mortality & multi-morbidity

Differences in HDL-related mortality risk between individuals with and without hypertension: a prospective cohort study in UK Biobank

J. Chen et. al, European Journal of Preventive Cardiology, 2023
Risk prediction, Cardiovascular disease

High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis

P. Wurtz et. al, European Heart Journal, 2012
Methods

bubbleHeatmap: an R package for visualization of Nightingale Health metabolomics datasets

R. Boxall et. al, Bioinformatics Advances, 2023
Diabetes

Serum Omega-6 Polyunsaturated Fatty Acids and the Metabolic Syndrome: A Longitudinal Population-based Cohort Study

M. Vanhala et. al, American Journal of Epidemiology, 2012
Obesity & bodyweight

Gender-Dependent Associations of Metabolite Profiles and Body Fat Distribution in a Healthy Population with Central Obesity: Towards Metabolomics Diagnostics

E. Szymańska et. al, OMICS: A Journal of Integrative Biology, 2012
Psychiatric disorders

Assessment of causal relationships between omega-3 and omega-6 polyunsaturated fatty acids in bipolar disorder: a 2-sample bidirectional mendelian randomization study

M. Zhang et. al, Food & Function, 2023
Cardiovascular disease

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis

P. Würtz et. al, Mol. BioSyst., 2010
Methods

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

P. Soininen et. al, The Analyst, 2009
Genetics, Cardiovascular disease

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

Y. Fan et. al, Scientific Reports, 2014
Ageing & dementia

Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles

N. Van Den Berg et. al, Nature Communications, 2023