Ageing & dementia

Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

O. Zeleznik et. al, Nature Communications, 2023
Ageing & dementia

Cross-sectionally Calculated Metabolic Aging Does Not Relate to Longitudinal Metabolic Changes—Support for Stratified Aging Models

M. Ala-Korpela et. al, The Journal of Clinical Endocrinology & Metabolism, 2023
Inflammation & immunity

Prediagnostic Glycoprotein Acetyl Levels and Incident and Recurrent Flare Risk Accounting for Serum Urate Levels: A Population‐Based, Prospective Study and Mendelian Randomization Analysis

A. Joshi et. al, Arthritis & Rheumatology, 2023
Diabetes

Sleep Patterns, Plasma Metabolome, and Risk of Incident Type 2 Diabetes Mellitus

Z. Zhuang et. al, The Journal of Clinical Endocrinology & Metabolism, 2023
Inflammation & immunity

Metabolic Signature of Healthy Lifestyle and Risk of Rheumatoid Arthritis: Observational and Mendelian Randomization Study

J. Zhang et. al, The American Journal of Clinical Nutrition, 2023
Cardiovascular disease

Assessment of valvular function in over 47,000 people using deep learning-based flow measurements

S. Kany et. al, 2023
Psychiatric disorders

Analysis of Plasma Metabolic Profile on Ganglion Cell–Inner Plexiform Layer Thickness With Mortality and Common Diseases

S. Yang et. al, JAMA Network Open, 2023
Maternal & child health

Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study

J. Zhao et. al, eBioMedicine, 2023
Psychiatric disorders

Glycoprotein acetyls and depression: Testing for directionality and potential causality using longitudinal data and Mendelian randomization analyses

D. Crick et. al, Journal of Affective Disorders, 2023
Cancer

Identifying metabolic features of colorectal cancer liability using Mendelian randomization

C. Bull et. al, eLife, 2023
Ageing & dementia

Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses

J. Mak et. al, Aging Cell, 2023
Cardiovascular disease

Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes

A. Schmidt et. al, Communications Medicine, 2023
Exposome & nutrition

Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals

N. Amin et. al, JAMA Psychiatry, 2023
Cardiovascular disease

Causal evidence for an ApoB-independent metabolomic risk profile associated with coronary artery disease

L. Ao et. al, 2023
Inflammation & immunity

Comparison of the stability of Glycoprotein Acetyls and high sensitivity C-reactive protein as markers of chronic inflammation