Ageing & dementia, Genetics

Investigating Causal Relations Between Circulating Metabolites and Alzheimer’s Disease: A Mendelian Randomization Study

S. Huang et. al, Journal of Alzheimer's Disease, 2022
Ageing & dementia

Longitudinal analysis of UK Biobank participants suggests age and APOE-dependent alterations of energy metabolism in development of dementia

J. Liu et. al, 2022
Exposome & nutrition

Diverging metabolic effects of 2 energy-restricted diets differing in nutrient quality: a 12-week randomized controlled trial in subjects with abdominal obesity

S. Schutte et. al, The American Journal of Clinical Nutrition, 2022
Diabetes, Genetics

Genome-wide discovery for diabetes-dependent triglycerides-associated loci

M. Selvaraj et. al, PLOS ONE, 2022
Maternal & child health

Early life infection and proinflammatory, atherogenic metabolomic and lipidomic profiles in infancy: a population-based cohort study

T. Mansell et. al, eLife, 2022
Diabetes

Circulating Metabolic Biomarkers Are Consistently Associated With Type 2 Diabetes Risk in Asian and European Populations

J. Seah et. al, The Journal of Clinical Endocrinology & Metabolism, 2022
Obesity & bodyweight

Sex-specific associations of adiposity with cardiometabolic traits in the UK: A multi–life stage cohort study with repeat metabolomics

L. O’Keeffe et. al, PLOS Medicine, 2022
Methods

metaboprep: an R package for preanalysis data description and processing

D. Hughes et. al, Bioinformatics, 2022
Medicines & trials, Genetics

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

T. Richardson et. al, PLOS Biology, 2022
Inflammation & immunity, Lung disease

Metabolic and Immune Markers for Precise Monitoring of COVID-19 Severity and Treatment

A. Rendeiro et. al, Frontiers in Immunology, 2022
Liver disease, Genetics

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease

P. Luukkonen et. al, Journal of Hepatology, 2021
Methods

1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints

D. Bizzarri et. al, eBioMedicine, 2021
Cardiovascular disease, Risk prediction

Serum metabolomics improve risk stratification for incident heart failure

R. Oexner et. al, 2023
Mortality & multi-morbidity

From plasma triglycerides to triglyceride metabolism: effects on mortality in the Copenhagen General Population Study

M. Johansen et. al, European Heart Journal, 2023
Cardiovascular disease

Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank study

E. Björnson et. al, European Heart Journal, 2023