Genetics, Diabetes, Cardiovascular disease

Using genetics to examine the overall and sex-specific associations of branch-chain amino acids and the valine metabolite, 3-hydroxyisobutyrate, with ischemic heart disease and diabetes: A two-sample Mendelian randomization study

J. Zhao et. al, Atherosclerosis, 2023
Cardiovascular disease

Discovery and validation of circulating stroke metabolites by NMR-based analyses using patients from the MISS and UK Biobank

M. Rout et. al, Neurochemistry International, 2023
Diabetes

Associations of Clinical Risk Factors and Novel Biomarkers With Age at Onset of Type 2 Diabetes

J. Chen et. al, The Journal of Clinical Endocrinology & Metabolism, 2023
Exposome & nutrition, Psychiatric disorders

Long-term ambient ozone, omega-3 fatty acid, genetic susceptibility, and risk of mental disorders among middle-aged and older adults in UK biobank

J. Jin et. al, Environmental Research, 2023
Ageing & dementia, Exposome & nutrition

Plasma Omega-3 Fatty Acids and Risk for Incident Dementia in the UK Biobank Study: A Closer Look

A. Sala-Vila et. al, Nutrients, 2023
Risk prediction, Ageing & dementia, Mortality & multi-morbidity

Metabolic biomarkers using nuclear magnetic resonance metabolomics assay for the prediction of aging-related disease risk and mortality: a prospective, longitudinal, observational, cohort study based on the UK Biobank

J. Lian et. al, GeroScience, 2023
Mortality & multi-morbidity, Cardiovascular disease

The relationship of fatty acids to ischaemic heart disease and lifespan in men and women using Mendelian randomization

C. Schooling et. al, International Journal of Epidemiology, 2023
Cardiovascular disease

Associations of circulating fatty acids with incident coronary heart disease: a prospective study of 89,242 individuals in UK Biobank

D. Jin et. al, BMC Cardiovascular Disorders, 2023
Cardiovascular disease, Exposome & nutrition

The Association of Metabolomic Profiles of a Healthy Lifestyle with Heart Failure Risk in a Prospective Study

Y. Ma et. al, Nutrients, 2023
Psychiatric disorders

A Machine Learning Analysis of Big Metabolomics Data for Classifying Depression: Model Development and Validation

S. Ma et. al, Biological Psychiatry, 2023
Genetics

Unraveling phenotypic variance in metabolic syndrome through multi-omics

L. Amente et. al, Human Genetics, 2023
Risk prediction, Genetics

Metabolomic profiles, polygenic risk scores and risk of rheumatoid arthritis: a population-based cohort study in the UK Biobank

X. Fang et. al, RMD Open, 2023
Cardiovascular disease, Genetics

Causal role of lipid metabolome on the risk of ischemic stroke, its etiological subtypes, and long-term outcome: A Mendelian randomization study

J. Martín-Campos et. al, Atherosclerosis, 2023
Genetics

Integrating GWAS summary statistics, individual-level genotypic and omic data to enhance the performance for large-scale trait imputation

J. Ren et. al, Human Molecular Genetics, 2023
Genetics

Leveraging omics data to boost the power of genome-wide association studies

Z. Lin et. al, Human Genetics and Genomics Advances, 2022