Diabetes

The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT)

L. Corbin et. al, Diabetologia, 2023
Inflammation & immunity, Lung disease, Genetics

Circulating Polyunsaturated Fatty Acids and COVID-19: A Prospective Cohort Study and Mendelian Randomization Analysis

Y. Sun et. al, Frontiers in Medicine, 2022
Cardiovascular disease, Genetics

Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants

M. Borges et. al, BMC Medicine, 2022
Cardiovascular disease, Ageing & dementia

Metabolic associations with stroke, dementia, and imaging markers of cerebral small vessel disease: a comprehensive metabolomics study

E. Harshfield et. al, 2022
Genetics, Ageing & dementia

Effects of genetic liability to Alzheimer’s disease on circulating metabolites across the life course

Genetics

Fifty-one novel and replicated GWAS loci for polyunsaturated and monounsaturated fatty acids in 124,024 Europeans

M. Francis et. al, 2022
Methods, Genetics

Sparse dimensionality reduction approaches in Mendelian randomisation with highly correlated exposures

V. Karageorgiou et. al, eLife, 2023
Ageing & dementia

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

E. Macdonald-Dunlop et. al, Aging, 2022
Genetics

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

C. Smith et. al, eLife, 2022
Mortality & multi-morbidity

Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank

H. Julkunen et. al, Nature Communications, 2023
Psychiatric disorders

Interplay of Human Metabolome and Gut Microbiome in Major Depression

N. Amin et. al, 2023
Ageing & dementia

Fat metabolism is associated with telomere length in six population-based studies

A. Van Der Spek et. al, Human Molecular Genetics, 2021
Methods

MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health’s 1H-NMR metabolomics data

D. Bizzarri et. al, Bioinformatics, 2022
Genetics, Methods

Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies

A. Niehues et. al, BMC Genomics, 2022
Genetics

Association between mitochondrial DNA haplogroups J and K, serum branched-chain amino acids and lowered capability for endurance exercise

J. Kiiskilä et. al, BMC Sports Science, Medicine and Rehabilitation, 2022