Mortality & multi-morbidity, Risk prediction, Methods, Ageing & dementia, Genetics

The MetaboHealth score is 40% heritable and is influenced by frailty status, BMI, and smoking in Swedish twins

L. Smulders et. al, GeroScience, 2026
Ageing & dementia

Distinct metabolic signatures of Alzheimer’s and Parkinson’s disease revealed through genetic overlap with metabolic markers

S. Stinson et. al, 2025
Psychiatric disorders

Shared genetic architecture between anorexia nervosa and metabolomic biomarkers suggest underlying causal pathways

C. Makowski et. al, 2025
Cardiovascular disease

A blood-based metabolomics study of cardiovascular diseases in Swedish twins reveals apolipoprotein B biology as important for myocardial infarction

A. Skovgaard et. al, GeroScience, 2026
Cardiovascular disease

Combined clinical, metabolomic, and polygenic scores for cardiovascular risk prediction

S. Ritchie et. al, European Heart Journal, 2025
Mortality & multi-morbidity, Risk prediction

Personal-MetaboHealth, an actionable health check in middle age, is improved by an effective lifestyle intervention in those at risk

N. Berg et. al, 2026
Genetics, Diabetes

Genetic regulation across germline and somatic variation on the Y chromosome contributes to type 2 diabetes

G. Sato et. al, Nature Medicine, 2026
Ageing & dementia

Elevated branched-chain amino acids linked to hippocampal volumes and cognitive improvement in mild cognitive impairment

H. Huang et. al, Brain Imaging and Behavior, 2026
Mortality & multi-morbidity

Multi-disease risk prediction models for population-scale personalised screening

R. Oexner et. al, 2026
Obesity & bodyweight, Maternal & child health, Genetics

Pro‑inflammatory insulin‑resistant lipid phenotype in down syndrome identified by 1H‑NMR metabolomics in obesity-matched African‑American children and young adults

H. Qu et. al, Scientific Reports, 2025
Exposome & nutrition, Obesity & bodyweight, Maternal & child health

Metabolic remodeling and the modulatory role of vitamin D deficiency in African American children and adolescents with obesity

H. Qu et. al, International Journal of Obesity, 2026
Inflammation & immunity, Mortality & multi-morbidity, Exposome & nutrition

Gut micro-organisms associated with health, nutrition and dietary interventions

F. Asnicar et. al, Nature, 2025
Diabetes, Inflammation & immunity

Associations of long-term cumulative C-reactive protein and glycoprotein acetyls concentrations in childhood, adolescence and adulthood with adulthood retinal microvascular structure

O. Repo et. al, Atherosclerosis, 2025
Ageing & dementia

MRI-based multi-organ clocks for healthy aging and disease assessment

H. Cao et. al, Nature Medicine, 2025
Ageing & dementia, Psychiatric disorders

Metabolomic ageing across mental and behavioural disorders

J. Mutz et. al, 2025