Exposome & nutrition

Deciphering the Relationship Between Circulating Metabolites and Osteoarthritis: A Comprehensive Genetic Correlation and Mendelian Randomization Studies

G. Yang et. al, International Journal of Medical Sciences, 2025
Inflammation & immunity

Metabolic signature of COVID-19 progression: potential prognostic markers for severity and outcome

H. Nguyen et. al, Metabolomics, 2025
Ageing & dementia, Mortality & multi-morbidity

Multi-organ metabolome biological age implicates cardiometabolic conditions and mortality risk

A. Zalesky et. al, Nature Communications, 2025
Genetics

Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers

D. Van Der Meer et. al, Nature Communications, 2025
Liver disease

Dissecting metabolic dysfunction- and alcohol-associated liver disease (MetALD) using proteomic and metabolomic profiles

J. Liu et. al, Journal of Hepatology, 2025
Psychiatric disorders

Association between ketone metabolism and the risk of depression: An observational and Mendelian randomization study

X. Dong et. al, Journal of Affective Disorders, 2025
Ageing & dementia

Prospective association between plasma amino acids and healthy aging in older adults

D. González‐Beltrán et. al, Journal of Internal Medicine, 2025
Mortality & multi-morbidity, Ageing & dementia

Association of Metabolomics With Incidence of Age-Related Macular Degeneration: The UK Biobank Study

J. Yu et. al, Investigative Ophthalmology & Visual Science, 2024
Diabetes

Metabolomic network reveals novel biomarkers for type 2 diabetes mellitus in the UK Biobank study

J. Liu et. al, Diabetes, Obesity and Metabolism, 2025
Maternal & child health

Levothyroxine treatment during pregnancy: a metabolomics study

O. Kärkkäinen et. al, 2025
Methods

Manifold fitting reveals metabolomic heterogeneity and disease associations in UK Biobank populations

B. Li et. al, Proceedings of the National Academy of Sciences, 2025
Liver disease

A plasma metabolome‐derived model predicts severe liver outcomes of nonalcoholic fatty liver disease in the UK Biobank

X. Xu et. al, Diabetes, Obesity and Metabolism, 2025
Methods

Cross-platform metabolomics imputation using importance-weighted autoencoders

A. Smith et. al, 2025
Ageing & dementia, Methods

Accelerated metabolomic ageing (MileAge) in mid-life predicts incident vascular, unspecified and all-cause dementia

J. Mutz et. al, 2025
Ageing & dementia, Mortality & multi-morbidity

Metabolic Profiling of Individuals with Missing Teeth and Tooth Loss

A. Halme et. al, Journal of Dental Research, 2025