Genetics, Cardiovascular disease

High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease

V. Zuber et. al, International Journal of Epidemiology, 2020
Diabetes

GlycA for long-term outcome in T2DM secondary prevention

B. Zierfuss et. al, Diabetes Research and Clinical Practice, 2020
Methods

Establishing reference intervals for triglyceride-containing lipoprotein subfraction metabolites measured using nuclear magnetic resonance spectroscopy in a UK population

R. Joshi et. al, Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2020
Genetics

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

M. Gomez-Alonso et. al, Clinical Epigenetics, 2021
Ageing & dementia, Genetics

Determinants of accelerated metabolomic and epigenetic aging in a UK cohort

O. Robinson et. al, Aging Cell, 2020
Maternal & child health, Diabetes

Cord serum metabolome and birth weight in patients with gestational diabetes treated with metformin, insulin, or diet alone

M. Huhtala et. al, BMJ Open Diabetes Research & Care, 2021
Ageing & dementia

Circulating metabolites are associated with brain atrophy and white matter hyperintensities

F. De Leeuw et. al, Alzheimer's & Dementia, 2020
Maternal & child health

Children with familial hypercholesterolemia display changes in LDL and HDL function: A cross‐sectional study

J. Christensen et. al, Journal of Internal Medicine, 2021
Maternal & child health, Cardiovascular disease, Inflammation & immunity

Childhood overeating is associated with adverse cardiometabolic and inflammatory profiles in adolescence

C. Hübel et. al, Scientific Reports, 2021
Diabetes, Ageing & dementia

Characterising frailty, metrics of continuous glucose monitoring, and mortality hazards in older adults with type 2 diabetes on insulin therapy (HARE): a prospective, observational cohort study

E. Fung et. al, The Lancet Healthy Longevity, 2021
Cardiovascular disease

Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: A cohort study

J. Bell et. al, PLOS Medicine, 2021
Mortality & multi-morbidity

Apt interpretation of comprehensive lipoprotein data in large-scale epidemiology: disclosure of fundamental structural and metabolic relationships

M. Ala-Korpela et. al, International Journal of Epidemiology, 2021
Ageing & dementia

An integrative study of five biological clocks in somatic and mental health

R. Jansen et. al, eLife, 2021
Maternal & child health

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health

S. Marttila et. al, Scientific Reports, 2021
Medicines & trials, Exposome & nutrition

Achievement of the Targets of the 20-Year Infancy-Onset Dietary Intervention—Association with Metabolic Profile from Childhood to Adulthood

M. Lehtovirta et. al, Nutrients, 2021