Cancer

Metabolomic landscape of overall and common cancers in the UK Biobank: A prospective cohort study

C. Hu et. al, International Journal of Cancer, 2024
Exposome & nutrition, Cardiovascular disease

Muesli Intake May Protect Against Coronary Artery Disease

J. Park et. al, JACC: Advances, 2024
Exposome & nutrition, Obesity & bodyweight

The association between body mass index and metabolite response to a liquid mixed meal challenge: a Mendelian randomization study

D. Hughes et. al, The American Journal of Clinical Nutrition, 2024
Ageing & dementia

Mendelian Randomization of Blood Metabolites Suggests Circulating Glutamine Protects Against Late-Onset Alzheimer’s Disease

F. Ramadan et. al, Journal of Alzheimer’s Disease, 2024
Exposome & nutrition, Mortality & multi-morbidity

Association of Plasma n-3 Polyunsaturated Fatty Acid Levels and the Prevalence of Frailty in Older Adults: A Cross-Sectional Analysis of UK Biobank

J. Kim et. al, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2024
Genetics, Mortality & multi-morbidity, Risk prediction

An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases

M. Benson et. al, 2024
Genetics

Genome-wide characterization of circulating metabolic biomarkers

M. Karjalainen et. al, Nature, 2024
Kidney disease

Blood metabolites mediate the impact of lifestyle factors on the risk of urolithiasis: a multivariate, mediation Mendelian randomization study

Z. Li et. al, Urolithiasis, 2024
Diabetes, Kidney disease

Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes Biobank

Q. Jin et. al, Diabetologia, 2024
Inflammation & immunity

Gut microbiota, circulating metabolites, and gallstone disease: a Mendelian randomization study

X. Hu et. al, Frontiers in Microbiology, 2024
Inflammation & immunity

Potential association of genetically predicted lipid and lipid-modifying drugs with rheumatoid arthritis: A Mendelian randomization study

Z. Huang et. al, PLOS ONE, 2024
Cardiovascular disease, Ageing & dementia

Correlations between the NMR Lipoprotein Profile, APOE Genotype, and Cholesterol Efflux Capacity of Fasting Plasma from Cognitively Healthy Elderly Adults

I. De Rojas et. al, International Journal of Molecular Sciences, 2023
Diabetes, Maternal & child health

Prediction of pre-diabetes and type 2 diabetes nine years postpartum using serum metabolome in pregnant women with gestational diabetes requiring pharmacological treatment

M. Huhtala et. al, Journal of Diabetes and its Complications, 2023
Methods

Sodium fluoride preserves blood metabolite integrity for biomarker discovery in large-scale, multi-site metabolomics investigations

W. Xiong et. al, The Analyst, 2024
Maternal & child health

Associations of polymetabolic risk of high maternal pre-pregnancy body mass index with pregnancy complications, birth outcomes, and early childhood neurodevelopment: findings from two pregnancy cohorts

P. Girchenko et. al, BMC Pregnancy and Childbirth, 2024