Obesity & bodyweight

Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change

P. Würtz et. al, PLoS Medicine, 2014
Liver disease

Ketone body production is differentially altered in steatosis and non‐alcoholic steatohepatitis in obese humans

V. Männistö et. al, Liver International, 2014
Diabetes, Genetics

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

J. Chambers et. al, The Lancet Diabetes & Endocrinology, 2015
Diabetes

Diabetes risk and amino acid profiles: cross-sectional and prospective analyses of ethnicity, amino acids and diabetes in a South Asian and European cohort from the SABRE (Southall And Brent REvisited) Study

T. Tillin et. al, Diabetologia, 2015
Diabetes

Associations of multiple lipoprotein and apolipoprotein measures with worsening of glycemia and incident type 2 diabetes in 6607 non-diabetic Finnish men

M. Fizelova et. al, Atherosclerosis, 2015
Liver disease

Adipose Tissue Dysfunction and Altered Systemic Amino Acid Metabolism Are Associated with Non-Alcoholic Fatty Liver Disease

S. Cheng et. al, PLOS ONE, 2015
Genetics, Diabetes, Cardiovascular disease

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

K. Beaney et. al, Cardiovascular Diabetology, 2016
Exposome & nutrition

The effect of standardized food intake on the association between BMI and 1H-NMR metabolites

B. Schutte et. al, Scientific Reports, 2016
Medicines & trials

Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study

D. Preiss et. al, Diabetic Medicine, 2016
Maternal & child health

Serum Amino Acid Profiles in Childhood Predict Triglyceride Level in Adulthood: A 7-Year Longitudinal Study in Girls

P. Wiklund et. al, The Journal of Clinical Endocrinology & Metabolism, 2016
Inflammation & immunity

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

V. Aho et. al, Scientific Reports, 2016
Genetics

Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol

T. Roman et. al, The American Journal of Human Genetics, 2015
Methods

metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

A. Cichonska et. al, Bioinformatics, 2016
Medicines & trials, Genetics

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

P. Würtz et. al, Journal of the American College of Cardiology, 2016
Genetics

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase–Independent Effects

F. Drenos et. al, Circulation: Cardiovascular Genetics, 2016