Cardiovascular disease

Per-Particle Triglyceride-Rich Lipoproteins Imply Higher Myocardial Infarction Risk Than Low-Density Lipoproteins: Copenhagen General Population Study

M. Johansen et. al, Arteriosclerosis, Thrombosis, and Vascular Biology, 2021
Exposome & nutrition, Genetics

Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism

R. Li-Gao et. al, Diabetes, 2021
Ageing & dementia

Profiling the metabolome of patients with dementia in the UK Biobank

J. Liu et. al, Alzheimer's & Dementia, 2021
Maternal & child health

Population epidemiology and concordance for plasma amino acids and precursors in 11–12-year-old children and their parents

S. Andraos et. al, Scientific Reports, 2021
Medicines & trials

Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

A. Schmidt et. al, Nature Communications, 2021
Diabetes

Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study

W. Wang et. al, Metabolomics, 2021
Cardiovascular disease

Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE

G. Robinson et. al, EBioMedicine, 2021
Cardiovascular disease

Dietary Interventions Reduce Traditional and Novel Cardiovascular Risk Markers by Altering the Gut Microbiome and Their Metabolites

A. Vijay et. al, Frontiers in Cardiovascular Medicine, 2021
Cardiovascular disease

Improved lipidomic profile mediates the effects of adherence to healthy lifestyles on coronary heart disease

J. Si et. al, eLife, 2021
Medicines & trials

Effects of dexmedetomidine, propofol, sevoflurane and S-ketamine on the human metabolome

A. Nummela et. al, European Journal of Anaesthesiology, 2021
Obesity & bodyweight

Mitochondrial bioenergetic pathways in blood leukocyte transcriptome decrease after intensive weight loss but are rescued following weight regain in female physique athletes

H. Sarin et. al, The FASEB Journal, 2021
Genetics, Methods

A Computationally Efficient Bayesian Seemingly Unrelated Regressions Model for High-Dimensional Quantitative Trait Loci Discovery

L. Bottolo et. al, Journal of the Royal Statistical Society Series C: Applied Statistics, 2021
Exposome & nutrition

NMR Metabolite Profiles in Male Meat-Eaters, Fish-Eaters, Vegetarians and Vegans, and Comparison with MS Metabolite Profiles

J. Schmidt et. al, Metabolites, 2021
Genetics

Novel protein-altering variants associated with serum apolipoprotein and lipid levels

Genetics

Assessing the contribution of rare-to-common protein-coding variants to circulating metabolic biomarker levels via 412,394 UK Biobank exome sequences

A. Nag et. al, 2021