Inflammation & immunity

Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency

M. Macpherson et. al, Journal of Clinical Immunology, 2023
Diabetes, Risk prediction

Metabolic fingerprinting on retinal pigment epithelium thickness for individualized risk stratification of type 2 diabetes mellitus

S. Yang et. al, Nature Communications, 2023
Psychiatric disorders

Metabolomics signatures of depression: the role of symptom profiles

H. De Kluiver et. al, Translational Psychiatry, 2023
Cardiovascular disease, Medicines & trials

Atherosclerosis Progression in the APPLE Trial Can Be Predicted in Young People With Juvenile‐Onset Systemic Lupus Erythematosus Using a Novel Lipid Metabolomic Signature

J. Peng et. al, Arthritis & Rheumatology, 2023
Cardiovascular disease, Genetics

SGLT2 inhibition, circulating metabolites, and atrial fibrillation: a Mendelian randomization study

J. Li et. al, Cardiovascular Diabetology, 2023
Genetics

Renoprotective effects of genetically proxied fibroblast growth factor 21: Mendelian randomization, proteome-wide and metabolome-wide association study

A. Giontella et. al, Metabolism, 2023
Cardiovascular disease

Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies

J. O’Keefe et. al, Stroke, 2023
Exposome & nutrition, Medicines & trials

The Effect of Carbohydrate Restriction on Lipids, Lipoproteins, and Nuclear Magnetic Resonance-Based Metabolites: CALIBER, a Randomised Parallel Trial

D. Mccullough et. al, Nutrients, 2023
Cardiovascular disease, Genetics

Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and Mice

S. Biswas et. al, 2023
Methods

Exploratory electronic health record analysis with ehrapy

L. Heumos et. al, 2023
Exposome & nutrition, Genetics

A Phenome-wide association study of genetically determined nicotine metabolism reveals novel links with health-related outcomes

J. Buchwald et. al, 2023
Mortality & multi-morbidity, Inflammation & immunity

Lower levels of small HDL particles associated with increased infectious disease morbidity and mortality: a population-based cohort study of 30 195 individuals

M. Harsløf et. al, Cardiovascular Research, 2022
Genetics, Cardiovascular disease

The Associations of Genetically Predicted Plasma Alanine with Coronary Artery Disease and its Risk Factors: A Mendelian Randomization Study

X. Huang et. al, The American Journal of Clinical Nutrition, 2023
Mortality & multi-morbidity

Divergent Survival Outcomes Associated with Elevated Branched-Chain Amino Acid Levels among Older Adults with or without Hypertension and Diabetes: A Validated, Prospective, Longitudinal Follow-Up Study

E. Fung et. al, Biomolecules, 2023
Genetics

A coding variant in the microsomal triglyceride transfer protein reduces both hepatic steatosis and plasma lipids

C. Schneider et. al, Alimentary Pharmacology & Therapeutics, 2023