Exposome & nutrition

Lifestyle‐Intervention‐Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter

M. Beekman et. al, Molecular Nutrition & Food Research, 2020
Medicines & trials

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas

J. Liu et. al, Nature Medicine, 2020
Cardiovascular disease

High-density lipoprotein cholesterol efflux capacity is not associated with atherosclerosis and prevalence of cardiovascular outcome: The CODAM study

T. Josefs et. al, Journal of Clinical Lipidology, 2019
Genetics

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

F. Hagenbeek et. al, Nature Communications, 2020
Genetics, Exposome & nutrition

Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome

O. Coltell et. al, Nutrients, 2020
Methods

EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics

J. Ekholm et. al, International Journal of Epidemiology, 2019
Cardiovascular disease

Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta‐Analysis in Up to 16 126 Participants

M. Borges et. al, Journal of the American Heart Association, 2020
Psychiatric disorders

Bidirectional longitudinal associations of omega-3 polyunsaturated fatty acid plasma levels with depressive disorders

C. Thesing et. al, Journal of Psychiatric Research, 2020
Cardiovascular disease

Causal Effects of Serum Levels of n-3 or n-6 Polyunsaturated Fatty Acids on Coronary Artery Disease: Mendelian Randomization Study

S. Park et. al, Nutrients, 2021
Genetics

Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile

D. Ibi et. al, Atherosclerosis, 2021
Cardiovascular disease

PCSK9 Activity Is Potentiated Through HDL Binding

S. Burnap et. al, Circulation Research, 2021
Cardiovascular disease

Targeted metabolomic profiling and prediction of cardiovascular events: a prospective study of patients with psoriatic arthritis and psoriasis

K. Colaco et. al, Annals of the Rheumatic Diseases, 2021
Exposome & nutrition

Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia

J. Auvinen et. al, Science Advances, 2021
Exposome & nutrition

Spousal associations of serum metabolomic profiles by nuclear magnetic resonance spectroscopy

K. Al Rashid et. al, Scientific Reports, 2021
Cardiovascular disease

Sex hormones drive changes in lipoprotein metabolism

G. Robinson et. al, iScience, 2021