Cancer

Identifying metabolic features of colorectal cancer liability using Mendelian randomization

C. Bull et. al, eLife, 2023
Ageing & dementia

Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses

J. Mak et. al, Aging Cell, 2023
Cardiovascular disease

Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes

A. Schmidt et. al, Communications Medicine, 2023
Exposome & nutrition

Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals

N. Amin et. al, JAMA Psychiatry, 2023
Cardiovascular disease

Causal evidence for an ApoB-independent metabolomic risk profile associated with coronary artery disease

L. Ao et. al, 2023
Inflammation & immunity

Comparison of the stability of Glycoprotein Acetyls and high sensitivity C-reactive protein as markers of chronic inflammation

Maternal & child health, Diabetes

Aberrations in the early pregnancy serum metabolic profile in women with prediabetes at two years postpartum

E. Muhli et. al, Metabolomics, 2023
Cancer

Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts

J. Rothwell et. al, BMC Medicine, 2023
Genetics

An atlas of genetic scores to predict multi-omic traits

Y. Xu et. al, Nature, 2023
Ageing & dementia

Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics

L. Kananen et. al, GeroScience, 2022
Maternal & child health

Association of physical activity with metabolic profile from adolescence to adulthood

M. Lehtovirta et. al, Scandinavian Journal of Medicine & Science in Sports, 2022
Obesity & bodyweight

Longitudinal metabolomics of increasing body-mass index and waist-hip ratio reveals two dynamic patterns of obesity pandemic

V. Mäkinen et. al, International Journal of Obesity, 2023
Genetics

Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank

A. Nag et. al, The American Journal of Human Genetics, 2023
Cardiovascular disease

Healthy lifestyle, plasma metabolites, and risk of cardiovascular disease among individuals with diabetes

Q. Lu et. al, Atherosclerosis, 2022
Liver disease

Causal relationships between genetically predicted circulating levels of amino acids and non-alcoholic fatty liver disease risk: a Mendelian randomisation study

J. Zhao et. al, 2023